RIFACIN 400 MG TABLET

DISCRIPTION

Rifacin-400 Tablet is a combination of (Rifaximin 400 mg) is a highly effective antibiotic used for treating bacterial infections of the intestine. It works by stopping the growth of certain bacteria without being significantly absorbed into the bloodstream. Rifacin-400 Tablet (Rifaximin 400 mg) is mainly prescribed for the treatment of traveler's diarrhea and irritable bowel syndrome with diarrhea (IBS-D) caused by specific strains of bacteria.

INDICATIONS 

• Traveler's Diarrhea: Rifacin-400 Tablet (Rifaximin 400 mg) used for the treatment of traveler's diarrhea caused by non-invasive strains of Escherichia coli. 

• Hepatic Encephalopathy: Rifacin-400 Tablet (Rifaximin 400 mg) used for the prevention of episodes of hepatic encephalopathy — a brain disorder marked by changes in thinking, behavior, and personality due to the accumulation of toxic substances in the brain from liver failure.

• Irritable Bowel Syndrome Associated Diarrhea (IBS-D): Rifacin-400 Tablet (Rifaximin 400 mg) used in the treatment of diarrhea associated with Irritable Bowel Syndrome, by targeting specific harmful bacteria in the gut and improving symptoms.
   

MECHANISM OF ACTION

Rifacin-400 Tablet (Rifaximin 400 mg) works by binding to the beta-subunit of bacterial DNA-dependent RNA polymerase, thereby inhibiting RNA synthesis and blocking transcription in susceptible bacteria. This action stops bacterial growth and controls infection locally in the intestine. Rifaximin also helps restore the natural balance of intestinal microflora. Additionally, it acts as a pregnane X receptor (PXR) activator, contributing to its anti-inflammatory effects.

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SIDE EFFECT OF RIFACIN-400 TABLET
Major & Minor side effects for Rifacin-400 Tablet

• Headache
• Peripheral oedema (leg swelling)
• Nausea
• Dizziness
• Fatigue
• Ascites (excess fluid build-up in the abdomen)
• Increased liver enzymes (ALT)

DRUG  INTERACTIONS

• Drug-Drug Interactions: Rifacin-400 Tablet (Rifaximin 400 mg)  may interact with drugs that affect the immune system (e.g., cyclosporine) and blood thinners (e.g., warfarin).

• Drug-Food Interactions: No significant drug-food interactions have been established for Rifacin-400 Tablet (Rifaximin 400 mg).

• Drug-Disease Interactions: Rifacin-400 Tablet (Rifaximin 400 mg)  should not be used by individuals with colitis, liver disease, or diarrhea caused by bacteria other than Escherichia coli.

PRECAUTION

Rifacin-400 Tablet (Rifaximin 400 mg)  should be used with caution in individuals with liver disease or intestinal conditions like colitis. It should not be used by people with diarrhea caused by bacteria other than E. coli. Pregnant or breastfeeding women should consult a doctor before using it. Always inform your doctor about any allergies or other medications you are taking.

DISCLAIMER
 
The information on this website is provided for general informational purposes only and is not medical advice. It is not a substitute for professional medical advice, diagnosis, or treatment. Consult a qualified healthcare provider for personalized advice. We do not endorse any specific products, treatments, or services mentioned.